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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
13.33
Human Site:
S754
Identified Species:
29.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S754
K
F
Y
L
E
F
H
S
S
C
L
E
S
F
V
Chimpanzee
Pan troglodytes
XP_526066
929
104074
E513
G
E
N
E
E
G
S
E
G
E
L
V
V
K
F
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
C773
F
I
E
F
Y
S
T
C
L
E
E
Y
K
K
S
Dog
Lupus familis
XP_542327
1264
138869
C779
F
I
E
F
Y
S
T
C
L
E
E
Y
K
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S757
K
F
Y
L
E
F
H
S
S
C
L
E
S
F
V
Rat
Rattus norvegicus
P97573
1190
133575
S756
K
F
Y
L
E
L
H
S
S
C
L
E
S
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
E603
S
P
K
A
P
R
K
E
R
Q
P
G
P
E
P
Chicken
Gallus gallus
XP_422567
1182
133482
S753
K
F
Y
I
E
F
H
S
S
C
L
E
S
F
V
Frog
Xenopus laevis
Q6P4S2
1019
115278
Q603
I
I
Q
K
I
K
Q
Q
Q
H
Q
E
L
L
P
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
C757
F
I
E
F
Y
S
T
C
L
E
E
F
K
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
E759
E
F
F
S
T
C
L
E
A
K
S
E
K
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
13.3
0
0
N.A.
100
93.3
N.A.
0
93.3
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
0
0
N.A.
100
93.3
N.A.
0
100
6.6
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
28
0
37
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
28
10
46
0
0
28
0
37
28
55
0
10
0
% E
% Phe:
28
46
10
28
0
28
0
0
0
0
0
10
0
37
10
% F
% Gly:
10
0
0
0
0
10
0
0
10
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
37
0
0
10
0
0
0
0
0
% H
% Ile:
10
37
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
37
0
10
10
0
10
10
0
0
10
0
0
37
37
0
% K
% Leu:
0
0
0
28
0
10
10
0
28
0
46
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
0
10
0
10
0
19
% P
% Gln:
0
0
10
0
0
0
10
10
10
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
0
28
10
37
37
0
10
0
37
10
28
% S
% Thr:
0
0
0
0
10
0
28
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
37
0
28
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _